Organocatalytic enantioselective desymmetrization of cyclic enones via phosphine promoted [3+2] annulations.
نویسندگان
چکیده
Phosphine catalyzed enantioselective [3+2] cyclizations on 4-substituted 2,6-diarylidenecyclohexanones and 2,4-diarylidene-bicyclo[3.1.0]hexan-3-ones take place with high diastereo- and enantioselectivity levels. The process affords spirocyclic compounds with excellent stereochemical control of up to five stereogenic centres.
منابع مشابه
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عنوان ژورنال:
- Chemical communications
دوره 47 3 شماره
صفحات -
تاریخ انتشار 2011